研究業績 / List of publications

2026年

・Shunpei Iwamoto, Yuya Nishizawa, Hayato Yokose, Osamu Kanie, Yosuke Okamura, Takahiro Muraoka*, Kenta Arai*, Beyond Folding Enzymes: A Redox-Active “Solid Chaperone” Unlocks Recyclable, HPLC-Free Oxidative Protein Folding, JACS Au, 2026, in press. (DOI: 10.1021/jacsau.5c01572)

・Kakeru Yamamoto, Kenta Arai*, An Initiator-Free Electrochemical Approach to Radical Thiol–Ene Coupling in a Microfluidic Reactor, Molecules., 2026, 31, 429. (DOI: 10.3390/molecules31030429)

Cover Gallery

Yuya Nishizawa,† Yuri Satoh,† Osamu Kanie and Kenta Arai*, Resin-supported cyclic telluride as a heterogeneous promoter of disulfide formation under solid–liquid biphasic conditions, New J. Chem. 2023, 47, 18537-18546 (†equal contribution) (DOI: 10.1039/D3NJ02646A) (Selected as front cover picture).

Rumi Mikami, Shunsuke Tsukagoshi, Yoshiki Oda, Kenta Arai*, S-Denitrosylase-like Activity of Cyclic Diselenides Conjugated with Xaa-His Dipeptide: Role of Proline Spacer as a Key Activity Booster. ChemBioChem, 2022, e202100394. in press. (DOI: 10.1002/cbic.202100394) (Selected as front cover picture)

Shunsuke Tsukagoshi, Rumi Mikami, Kenta Arai*, Basic amino acid conjugates of 1,2‐diselenan‐4‐amine with protein disulfide isomerase‐like functions as a manipulator of protein quality control, Chem Asian J. 2020, 15, pp. 2646–2652. (Selected as Very Important Paper and front cover picture)

Kenta Arai, Takahiko Matsunaga, Haruhito Ueno, Nozomi Akahoshi, Yuumi Sato, Gaurango Chakrabarty, Govindasamy Mugesh, Michio Iwaoka Modeling Thioredoxin Reductase-like Activity Using Cyclic Selenenyl Sulfides: Participation of an NH...Se Hydrogen Bond through Stabilization of the Mixed Se–S Intermediate. Chem. Eur. J. 2019,25,pp. 12751–12760.

Kenta Arai,* Yuui Osaka, Masahiro Haneda, Yuumi Sato, Cyclic telluride reagents with remarkable glutathione peroxidase-like activity for purification-free synthesis of highly pure organodisulfides, Catal. Sci. Technol., 2019, 9, pp. 3647-3655. (selected as backcover picture of the issue)

Kenta Arai, Kenji Moriai, Akinobu Ogawa, Michio Iwaoka, An Amphiphilic Selenide Catalyst Behaves Like a Hybrid Mimic of Protein Disulfide Isomerase and Glutathione Peroxidase 7. Chem. Asian J., 2014, 9, pp.3464-3471. (selected as backcover picture of the issue)

Kenta Arai, Kenichi Dedachi, Michio Iwaoka
Rapid and Quantitative Disulfide Bond Formation for a Polypeptide Chain Using a Cyclic Selenoxide Reagent in an Aqueous Medium. Chem. Eur. J., 2011, 17, pp.481–485. (selected as VIP and Front-Cover picture)

東海大学　先進生命科学研究所

荒井　堅太　研究室

～生物物理化学、生命化学、有機合成化学～

研究業績 / List of publications

Cover Gallery

Shunsuke Tsukagoshi, Rumi Mikami, Kenta Arai*, Basic amino acid conjugates of 1,2‐diselenan‐4‐amine with protein disulfide isomerase‐like functions as a manipulator of protein quality control, Chem Asian J. 2020, 15, pp. 2646–2652. (Selected as Very Important Paper and front cover picture)

Kenta Arai,* Yuui Osaka, Masahiro Haneda, Yuumi Sato, Cyclic telluride reagents with remarkable glutathione peroxidase-like activity for purification-free synthesis of highly pure organodisulfides, Catal. Sci. Technol., 2019, 9, pp. 3647-3655. (selected as backcover picture of the issue)

Kenta Arai, Kenji Moriai, Akinobu Ogawa, Michio Iwaoka, An Amphiphilic Selenide Catalyst Behaves Like a Hybrid Mimic of Protein Disulfide Isomerase and Glutathione Peroxidase 7. Chem. Asian J., 2014, 9, pp.3464-3471. (selected as backcover picture of the issue)

Kenta Arai, Kenichi Dedachi, Michio Iwaoka
Rapid and Quantitative Disulfide Bond Formation for a Polypeptide Chain Using a Cyclic Selenoxide Reagent in an Aqueous Medium. Chem. Eur. J., 2011, 17, pp.481–485. (selected as VIP and Front-Cover picture)

研究業績 / List of publications

Cover Gallery

Kenta Arai,* Yuui Osaka, Masahiro Haneda, Yuumi Sato, Cyclic telluride reagents with remarkable glutathione peroxidase-like activity for purification-free synthesis of highly pure organodisulfides, Catal. Sci. Technol., 2019, 9, pp. 3647-3655. (selected as backcover picture of the issue)

Kenta Arai, Kenji Moriai, Akinobu Ogawa, Michio Iwaoka, An Amphiphilic Selenide Catalyst Behaves Like a Hybrid Mimic of Protein Disulfide Isomerase and Glutathione Peroxidase 7. Chem. Asian J., 2014, 9, pp.3464-3471. (selected as backcover picture of the issue)

Kenta Arai, Kenichi Dedachi, Michio Iwaoka Rapid and Quantitative Disulfide Bond Formation for a Polypeptide Chain Using a Cyclic Selenoxide Reagent in an Aqueous Medium. Chem. Eur. J., 2011, 17, pp.481–485. (selected as VIP and Front-Cover picture)

Kenta Arai, Kenichi Dedachi, Michio Iwaoka
Rapid and Quantitative Disulfide Bond Formation for a Polypeptide Chain Using a Cyclic Selenoxide Reagent in an Aqueous Medium. Chem. Eur. J., 2011, 17, pp.481–485. (selected as VIP and Front-Cover picture)